Nicardipine hydrochloride

Nicardipine hydrochloride is a calcium channel blocker of the dihydropyridine class, primarily used to treat hypertension and angina. It functions by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, causing vasodilation, reduced systemic vascular resistance, and decreased blood pressure. Nicardipine is often used in both oral and intravenous forms, especially in emergency settings like hypertensive crises due to its rapid onset of action.

InChI:InChI=1/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H